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Spice is a fictional drug in Tom Clancy's The Division 2. Throughout Washington, D.C., players will find drug labs, drug-making paraphernalia and chemicals used by the Hyenas faction.

The drug seems to have brief human-enhancing properties that enable the Hyenas to deny pain, increasing their health. It also, however, makes the Hyenas the most agressive and less tactical faciton of D.C.

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